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Phospho NF-kB p65 (Ser276) Antibody

Affinity purified rabbit polyclonal antibody to detect phosphorylation of NF-kB p65 at Ser276 in Human, Mouse, Rat, Bovine, Monkey, Porcine samples
Catalog #: A1953
$325.00

Product Details

Size 100 µl
Antibody Target Phospho NF-kappaB p65 (Ser276)
Alternate Name NFKB3; Transcription factor p65; Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
Host Rabbit
Antibody Type Polyclonal
Isotype IgG
Accession # Q04206
Gene ID 5970
Appearance Colorless liquid
Formulation In 0.42% Potassium phosphate, 0.87% NaCl, pH 7.3, 30% glycerol, and 0.01% sodium azide
Purification Affinity purified
Species Reactivity Bovine, Porcine, Rat, Monkey, Mouse, Human
Application Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting
Application & Usage WB 1:500 - 1:1000, IHC 1:100 - 1:200, IP 1:10 - 1:100
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.


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