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Phospho IRF3 (Ser385) Antibody

Affinity purified rabbit polyclonal antibody to detect phosphorylation of IRF3 at Ser385 in human, mouse, bovine and porcine samples
Catalog #: A1983
$325.00

Product Details

Size 100 µl
Antibody Target Phospho IRF3 (Ser385)
Alternate Name Interferon regulatory factor 3; IRF-3
Host Rabbit
Antibody Type Polyclonal
Isotype IgG
Accession # Q14653
Gene ID 3661
Appearance Colorless liquid
Formulation In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide
Purification Affinity purified
Species Reactivity Bovine, Porcine, Mouse, Human
Application Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blotting
Application & Usage WB 1:500 - 1:1000, IHC 1:100 - 1:200, IF 1:100 - 1:500
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.


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