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Phospho Histone H3 (Ser10) Antibody

Affinity purified rabbit polyclonal antibody to detect phosphorylation of Histone H3 at Ser10 in human samples
Catalog #: A1943
$285.00

Product Details

Size 100 µl
Antibody Target Phospho Histone H3 (Ser10)
Alternate Name HIST3H3; H3.4; H3/g; H3FT; H3t; histone H3.1t
Host Rabbit
Antibody Type Polyclonal
Isotype IgG
Immunogen A synthetic phosphorylated peptide around Ser10 of human Histone H3
Accession # Q16695
Gene ID 8290
Appearance Liquid
Formulation In PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Affinity purified
Species Reactivity Human
Application Western Blotting
Application & Usage WB 1:500 - 1:2000
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intron-less and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack poly A tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.


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