Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

Phospho-Erk1/2 Antibody

based on 1 citations in multiple journalsPhospho-Erk1/2 Antibody14.1 4
Catalog #: 3441

In stock

$325.00

Product Details

Cat # +Size 3441-100
Size 100 µg
Antibody Target Phospho-Erk1/2 (p44/p42 MAPK)
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic phospho-peptide surrounding Thr202/Tyr204 of human P44MAP kinase
Accession # P63086
Gene ID 116590
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation 100 µg (0.5 mg/ml) purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% thimerosal.
Purification Affinity purified
Species Reactivity Human, mouse, rat
Application Western blot, Immunoprecipitation, Immunohistochemistry
Application & Usage Western blotting (0.5-4µg/ml), immunoprecipitation(10-20 µg/ml),and Immunohistochemistry (10-20 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes Phosphorylated p42 and p44 (Erk1 and Erk2).
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Both p44 and p42 MAP kinases (Erk1 and Erk2) function in a protein kinase cascade that plays a critical role in the regulation of cell growth and differentiation. Activation of MAP kinases occurs throμgh phosphorylation of threonine and tyrosine (202 and 204 of human MAP kinase [Erk1] or 183 and 185 of rat Erk2) at the sequence T*EY* by a single upstream MAP kinase kinase (MEK). Both kinases are known to weakly autophosphorylate on tyrosine.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.

Than et al., Apelin Attenuates Oxidative Stress in Human Adipocytes. J. Biol. Chem., Feb 2014; 289: 3763 - 3774.
Aung Than et al., Control of Adipogenesis by the Autocrine Interplays between Angiotensin 1–7/Mas Receptor and Angiotensin II/AT1 Receptor Signaling Pathways. J. Biol. Chem., May 2013; 288: 15520 - 15531.
For more citations of this product click here