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Phospho ER-alpha (Ser167) Antibody

Affinity purified rabbit polyclonal antibody to detect phosphorylation of ER-alpha at Ser167 in human samples
Catalog #: A1948
$285.00

Product Details

Size 100 µl
Antibody Target Phospho ER-alpha (Ser167)
Alternate Name ESR1; ER; ESR; ESRA; ESTRR; Era; NR3A1; estrogen receptor
Host Rabbit
Antibody Type Polyclonal
Isotype IgG
Immunogen A phospho specific peptide corresponding to residues surrounding Ser167 of human ER-alpha
Accession # P03372
Gene ID 2099
Appearance Liquid
Formulation In PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Affinity purified
Species Reactivity Human
Application Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blotting
Application & Usage IF 1:100 - 1:200, IHC 1:50 - 1:100, WB 1:500 - 1:2000
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.


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