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Phospho EIF4EBP1 (Thr36) Antibody

Affinity purified rabbit polyclonal antibody to detect phosphorylation of EIF4EBP1 at Thr36 in human, mouse and rat samples
Catalog #: A1945
$285.00

Product Details

Size 100 µl
Antibody Target Phospho EIF4EBP1 (Thr36)
Alternate Name EIF4EBP1; 4E-BP1; 4EBP1; BP-1; PHAS-I; eukaryotic translation initiation factor 4E-binding protein 1
Host Rabbit
Antibody Type Polyclonal
Isotype IgG
Immunogen A phospho specific peptide corresponding to residues surrounding Thr36 of human EIF4EBP1
Accession # Q13541
Gene ID 1978
Appearance Liquid
Formulation In PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Affinity purified
Species Reactivity Rat, Mouse, Human
Application Western Blotting
Application & Usage WB 1:500 - 1:2000
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multi-subunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.


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