Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

Phospho-AMPKα1 (Ser496) Antibody

Polyclonal antibody to detect endogenous levels of AMPKα1 protein when phosphorylated at Ser496 in human, mouse and rat.
Catalog #: A1247
$285.00

Product Details

Cat # +Size A1247-100
Size 100 µl
Antibody Target PRKAA1
Alternate Name PRKAA1; AMPK1; 5'-AMP-activated protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; Tau-protein kinase PRKAA1
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthesized peptide derived from human AMPKα1 around the phosphorylation site of S496 (420-500aa)
Accession # Q13131
Gene ID 5562
Appearance Colorless liquid
Formulation In PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Purification Affinity-chromatography using epitope-specific immunogen
Species Reactivity Human, mouse , rat
Application WB, ELISA, IHC
Positive Control WB: HeLa cell lysate
Application & Usage WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000
Handling The antibody solution should be gently mixed before use
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. Acts as a key regulator of cell growth and proliferation by phosphorylating TSC2, RPTOR and ATG1/ULK1: in response to nutrient limitation, negatively regulates the mTORC1 complex by phosphorylating RPTOR component of the mTORC1 complex and by phosphorylating and activating TSC2.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.