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Phospho-Akt2 (Ser474) Antibody

Polyclonal antibody to detect endogenous levels of Akt2 protein phosphorylated at S474 in human, mouse and rat.
Catalog #: A1246
$285.00

Product Details

Cat # +Size A1246-100
Size 100 µl
Antibody Target AKT2
Alternate Name AKT2; RAC-beta serine/threonine-protein kinase; Protein kinase Akt-2; Protein kinase B beta; PKB beta; RAC-PK-beta
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthesized peptide derived from human Akt2 around the phosphorylation site of S474
Accession # P31751
Gene ID 208
Appearance Colorless liquid
Formulation In PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Purification Affinity-chromatography using epitope-specific immunogen
Species Reactivity Human, mouse , rat
Application WB, ELISA, IHC
Positive Control WB: Mouse brain lysate, 293 cell lysate
Application & Usage WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000
Handling The antibody solution should be gently mixed before use
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

AKT2 is a putative oncogenic protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. Furthermore, AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression of AKT2 contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT2 is a general protein kinase capable of phophorylating several known proteins.


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