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Product Details
| Cat # +Size | A1246-100 |
|---|---|
| Size | 100 µl |
| Antibody Target | AKT2 |
| Alternate Name | AKT2; RAC-beta serine/threonine-protein kinase; Protein kinase Akt-2; Protein kinase B beta; PKB beta; RAC-PK-beta |
| Host | Rabbit |
| Antibody Type | Polyclonal |
| Isotype | Rabbit IgG |
| Immunogen | Synthesized peptide derived from human Akt2 around the phosphorylation site of S474 |
| Accession # | P31751 |
| Gene ID | 208 |
| Appearance | Colorless liquid |
| Formulation | In PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
| Purification | Affinity-chromatography using epitope-specific immunogen |
| Species Reactivity | Human, mouse , rat |
| Application | WB, ELISA, IHC |
| Positive Control | WB: Mouse brain lysate, 293 cell lysate |
| Application & Usage | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000 |
| Handling | The antibody solution should be gently mixed before use |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not to be used in humans |
Details
AKT2 is a putative oncogenic protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. Furthermore, AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression of AKT2 contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT2 is a general protein kinase capable of phophorylating several known proteins.
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