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Phospho ACACA (Ser79) Antibody

Affinity purified rabbit polyclonal antibody to detect phosphorylation of ACACA at Ser79 in human, mouse and rat samples
Catalog #: A1941
$285.00

Product Details

Size 100 µl
Antibody Target Phospho ACACA (Ser79)
Alternate Name ACACA; ACAC; ACACAD; ACC; ACC1; ACCA; acetyl-CoA carboxylase 1
Host Rabbit
Antibody Type Polyclonal
Isotype IgG
Immunogen A phospho specific peptide corresponding to residues surrounding Ser79 of human ACACA
Accession # Q13085
Gene ID 31
Appearance Liquid
Formulation In PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Affinity purified
Species Reactivity Rat, Mouse, Human
Application Western Blotting
Application & Usage WB 1:500 - 1:2000
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.


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