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PF74

A HIV-1 inhibitor
Catalog #: B2369

In stock

SKU-Size Size Price Qty
B2369-5 5 mg
$115.00
B2369-25 25 mg
$455.00
More Sizes Get Quote

Product Details

Alternate Name PF-3450074, PF-74, 2-Methyl-N-[(1S)-2-(methylphenylamino)-2-oxo-1-(phenylmethyl)ethyl]- 1H-indole-3-acetamide
Appearance Crystalline solid
CAS # 1352879-65-2
Molecular Formula C₂₇H₂₇N₃O₂
Molecular Weight 525.53
Purity ≥98%
Solubility 5 mg/ml in DMSO
SMILES CC1=C(C2=CC=CC=C2N1)CC(=O)NC(CC3=CC=CC=C3)C(=O)N(C)C4=CC=CC=C4
InChi InChI=1S/C27H27N3O2/c1-19-23(22-15-9-10-16-24(22)28-19)18-26(31)29-25(17-20-11-5-3-6-12-20)27(32)30(2)21-13-7-4-8-14-21/h3-16,25,28H,17-18H2,1-2H3,(H,29,31)/t25-/m0/s1
InChi Key ACDFWSNAQWFRRF-VWLOTQADSA-N
PubChem CID 49800090
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

PF74 is a HIV-1 inhibitor that targets HIV capsid protein. PF74 binds specifically to HIV-1 particles and triggers premature HIV-1 uncoating in target cells. PF74 acts at an early stage of HIV-1 infection and inhibits reverse transcription in target cells.


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