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Product Details
| Alternate Name | PF-4989216, PF4989216; PF 4989216; 4-(4-cyano-2-fluorophenyl)-2-morpholin-4-yl-5-(1H-1,2,4-triazol-5-yl)thiophene-3-carbonitrile |
|---|---|
| Appearance | Solid |
| CAS # | 1276553-09-3 |
| Molecular Formula | C₁₈H₁₃FN₆OS |
| Molecular Weight | 380.4 |
| Purity | >98% |
| Solubility | DMSO |
| SMILES | C1COCCN1C2=C(C(=C(S2)C3=NC=NN3)C4=C(C=C(C=C4)C#N)F)C#N |
| InChi | InChI=1S/C18H13FN6OS/c19-14-7-11(8-20)1-2-12(14)15-13(9-21)18(25-3-5-26-6-4-25)27-16(15)17-22-10-23-24-17/h1-2,7,10H,3-6H2,(H,22,23,24) |
| InChi Key | MUENOTXSRZEFJV-UHFFFAOYSA-N |
| PubChem CID | 51033720 |
| Handling | Protect from air and light |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
PF-4989216 is a novel potent and selective PI3K inhibitor. PF-4989216 inhibits PI3Kalpha (Ki=0.6 nM) and mTOR (Ki=1440 nM).
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