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Product Details
| Alternate Name | trans-4-[4-(4-Amino-7,8-dihydro-5-oxopyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl]-cyclohexaneacetic acid, PF04620110 |
|---|---|
| Peptide Sequence | N/A |
| Appearance | Off-white solid |
| CAS # | 1109276-89-2 |
| Molecular Formula | C₂₁H₂₄N₄O₄ |
| Molecular Weight | 396.44 |
| Purity | ≥98% |
| Solubility | >7 mg/ml in DMSO |
| SMILES | C1CC(CCC1CC(=O)O)C2=CC=C(C=C2)N3CCOC4=NC=NC(=C4C3=O)N |
| InChi | InChI=1S/C21H24N4O4/c22-19-18-20(24-12-23-19)29-10-9-25(21(18)28)16-7-5-15(6-8-16)14-3-1-13(2-4-14)11-17(26)27/h5-8,12-14H,1-4,9-11H2,(H,26,27)(H2,22,23,24) |
| InChi Key | GEVVQZHMFVFGLN-UHFFFAOYSA-N |
| PubChem CID | 46926360 |
| Handling | Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure. |
| Storage Conditions | -20ºC |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
PF-04620110 is a potent and selective Acyl-CoA:diacylglycerol acyltransferase-1 (DGAT-1) inhibitor with (IC₅₀ = 19 nM).
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