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PF-4989216

A novel potent and selective PI3K inhibitor
Catalog #: B1659

In stock

SKU-Size Size Price Qty
B1659-5 5 mg
$120.00
B1659-25 25 mg
$450.00

Product Details

Alternate Name PF-4989216, PF4989216; PF 4989216; 4-(4-cyano-2-fluorophenyl)-2-morpholin-4-yl-5-(1H-1,2,4-triazol-5-yl)thiophene-3-carbonitrile
Appearance Solid
CAS # 1276553-09-3
Molecular Formula C₁₈H₁₃FN₆OS
Molecular Weight 380.4
Purity >98%
Solubility DMSO
SMILES C1COCCN1C2=C(C(=C(S2)C3=NC=NN3)C4=C(C=C(C=C4)C#N)F)C#N
InChi InChI=1S/C18H13FN6OS/c19-14-7-11(8-20)1-2-12(14)15-13(9-21)18(25-3-5-26-6-4-25)27-16(15)17-22-10-23-24-17/h1-2,7,10H,3-6H2,(H,22,23,24)
InChi Key MUENOTXSRZEFJV-UHFFFAOYSA-N
PubChem CID 51033720
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

PF-4989216 is a novel potent and selective PI3K inhibitor. PF-4989216 inhibits PI3Kalpha (Ki=0.6 nM) and mTOR (Ki=1440 nM).


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