A dopamine receptor antagonist
Catalog #: B3115 | abID:

Product Details

Alternate Name Trilafon; Etaperazine; Chlorpiprazine; 2-[4-[3-(2-chlorophenothiazin-10-yl)propyl]piperazin-1-yl]ethanol; 2-Chloro-10-3-(1-(2-hydroxyethyl)-4-piperazinyl)propyl phenothiazine
Appearance White to off-white powder
CAS # 58-39-9
Molecular Formula C₂₁H₂₆ClN₃OS
Molecular Weight 403.97
Purity ≥ 97%
Solubility ~20 mg/ml in DMSO, ~5 mg/ml in Ethanol, ~30 mg/ml in DMF
InChi InChI=1S/C21H26ClN3OS/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)27-21)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2
PubChem CID 4748
MDL Number MFCD00056798
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Perphenazine is a dopamine receptor antagonist. It binds to Dopamine receptors D₂, D₃ and D₄ with Ki values of 0.56 nM, 0.43 nM and 28.5 nM respectively. It also binds to serotonin receptors 5-HT1A, 5-HT2A, 5-HT2C, 5-HT6 and 5-HT7 with Ki values of 421 nM, 5.6 nM, 132 nM, 17 and 23 nM respectively. It is used as an antipsychotic drug.

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