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Penicillin G potassium, USP

An antibiotic and selection agent
Catalog #: 2504
SKU-Size Size Price Qty
2504-25 25 MU
2504-100 100 MU
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Product Details

Alternate Name Benzylpenicillin potassium salt
Appearance White to off-white powder
CAS # 113-98-4
Molecular Formula C₁₆H₁₇KN₂O₄S
Molecular Weight 372.49
Purity 1440-1680 u/mg
Solubility H₂O (100 mg/ml)
SMILES CC1(C(N2C(S1)C(C2=O)NC(=O)CC3=CC=CC=C3)C(=O)[O-])C.[K+]
InChi InChI=1S/C16H18N2O4S.K/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1
PubChem CID 23664709
MDL Number MFCD00036193
Handling Protect from air and moisture
Storage Conditions 4°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Penicillin G potassium is a member of the β-lactam antibiotics. β-Lactams interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBP’s are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Resistance to β-lactams is commonly due to cells containing plasmid encoded β-lactamases. Penicillin can be used as a selective agent in several types of isolation media.

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