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Product Details
| Alternate Name | Benzylpenicillin potassium salt |
|---|---|
| Appearance | White to off-white powder |
| CAS # | 113-98-4 |
| Molecular Formula | C₁₆H₁₇KN₂O₄S |
| Molecular Weight | 372.49 |
| Purity | 1440-1680 u/mg |
| Solubility | H₂O (100 mg/ml) |
| SMILES | CC1(C(N2C(S1)C(C2=O)NC(=O)CC3=CC=CC=C3)C(=O)[O-])C.[K+] |
| InChi | InChI=1S/C16H18N2O4S.K/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1 |
| InChi Key | IYNDLOXRXUOGIU-LQDWTQKMSA-M |
| PubChem CID | 23664709 |
| MDL Number | MFCD00036193 |
| Handling | Protect from air and moisture |
| Storage Conditions | 4°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Penicillin G potassium is a member of the β-lactam antibiotics. β-Lactams interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBP’s are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Resistance to β-lactams is commonly due to cells containing plasmid encoded β-lactamases. Penicillin can be used as a selective agent in several types of isolation media.
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