Product Details
| Cat # +Size | 1676-100 |
|---|---|
| Size | 100 mg |
| Alternate Name | Pyrrolidinedithiocarbamate Ammonium; PDC; APDC |
| Appearance | White solid |
| CAS # | 5108-96-3 |
| Molecular Formula | C₅H₉NS₂.NH₃ |
| Molecular Weight | 164.28 |
| Purity | ≥98% |
| Solubility | DMSO (15 mg/ml) and H₂O (1 mg/ml) |
| SMILES | C1CCN(C1)C(=S)[S-].[NH4+] |
| InChi | InChI=1S/C5H9NS2.H3N/c7-5(8)6-3-1-2-4-6;/h1-4H2,(H,7,8);1H3 |
| InChi Key | MDDIUTVUBYEEEM-UHFFFAOYSA-N |
| PubChem CID | 517348 |
| MDL Number | MFCD00012720 |
| Handling | Protect from air and moisture |
| Storage Conditions | 4°C |
| Shipping Conditions | RT |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
An antioxidant and an inhibitor of NF-kB; prevents induction of nitric oxide synthase (NOS) by inhibiting translation of NOS mRNA; induces apoptosis in rat smooth muscle cells and inhibits apoptosis in leukemia HL-60 cells. Also inhibits breast cancer stem-like cells by blocking the NF-kB activity in MCF7 sphere and MCF7 cells.
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Zhang, L.W et al. (2016) Interleukin-17 Impairs Salivary Tight Junction Integrity in Sjögren's Syndrome. J Dent Res. 2016 Jul;95(7):784-92.
Li et al., Activation of decidual invariant natural killer T cells promotes lipopolysaccharide-induced preterm birth. Mol. Hum. Reprod., Apr 2015; 21: 369 - 381.
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