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PDGF-BB, murine recombinant

based on 1 citations in multiple journalsPDGF-BB, murine recombinant14.1 4
A growth factor that regulates cell growth and division
Catalog #: 4489
SKU-Size Size Price Qty
4489-10 10 μg
$190.00
4489-1000 1 mg
$4,650.00
4489-50 50 μg
$595.00
More Sizes Get Quote

Product Details

Alternate Name Glioma-derived growth factor, GDGF, Osteosarcoma-derived Growth Factor, ODGF, SIS, SSV, PDGF2, c-sis, FLJ12858, PDGF-BB, PDGF B-chain, Platelet-derived growth factor β polypeptide, Becaplermin.
Gene Symbol PDGFB
Gene ID 18591
Accession # P31240
Source E. coli
Appearance Lyophilized protein
Physical Form Description Lyophilized with no additives
Molecular Weight 24.4 kDa
Purity by SDS-PAGE ≥95%
Purity by ≥95%
Endotoxin Level <0.1 ng/μg
Biological Activity The ED₅₀ as determined by the dose-dependent proliferation of murine BALB/c 3T3 cells is < 2 ng/ml.
Reconstitution Instructions Reconstitute in sterile 100mM acetic acid and 0.1% BSA to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Recombinant mouse Platelet Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle and connective tissue. PDGF, which is composed of a homodimeric, non-glycosylated, polypeptide of 109 amino acids and having a molecular mass of 24.4 kDa.


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Hamada, Y. et. al. In vivo imaging of the molecular distribution of the VEGF receptor during angiogenesis in a mouse model of ischemia. Blood, Sep 2011; 118: e93 - e100.
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