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PDGF-AB, human recombinant

A growth factor that regulates cell growth and division
Catalog #: 4485
SKU-Size Size Price Qty
4485-10 10 μg
$260.00
4485-50 50 μg
$815.00
4485-1000 1 mg
$6,350.00
More Sizes Get Quote

Product Details

Alternate Name Glioma-derived growth factor, GDGF, Osteosarcoma-derived Growth Factor, ODGF, PDGF-AB, Beta platelet-derived growth factor receptor, CD140 antigen-like family member B, Platelet-derived growth factor receptor 1
Source E. coli
Appearance Lyophilized protein
Physical Form Description Lyophilized with no additives
Molecular Weight 25.5 kDa
Purity by SDS-PAGE ≥98%
Purity by ≥98%
Endotoxin Level <0.1 ng/μg
Biological Activity The ED₅₀ as determined by the dose-dependent stimulation of thymidine uptake by BALB/c 3T3 cells is < 1 ng/ml, corresponding to a specific activity of >1 x 10⁶ units/mg.
Reconstitution Instructions Reconstitute in 10 mM acetic acid to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Platelet Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle and connective tissue. PDGF, which is composed of a dimer of two chains termed the A chain and B chain, can be present as AA or BB homodimers or as an AB heterodimer. Human PDGF-AB is a 25.5 kDa heterodimer protein consisting of a 13.3 kDa A chain and a 12.2 kDa B chain.


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