Product Details
| Alternate Name | CI-1040 |
|---|---|
| Appearance | Crystalline solid |
| CAS # | 212631-79-3 |
| Molecular Formula | C₁₇H₁₄ClF₂IN₂O₂ |
| Molecular Weight | 478.67 |
| Purity | ≥99% by HPLC |
| Solubility | DMSO (600 mg/ml) |
| SMILES | C1CC1CONC(=O)C2=C(C(=C(C=C2)F)F)NC3=C(C=C(C=C3)I)Cl |
| InChi | InChI=1S/C17H14ClF2IN2O2/c18-12-7-10(21)3-6-14(12)22-16-11(4-5-13(19)15(16)20)17(24)23-25-8-9-1-2-9/h3-7,9,22H,1-2,8H2,(H,23,24) |
| InChi Key | GFMMXOIFOQCCGU-UHFFFAOYSA-N |
| PubChem CID | 6918454 |
| MDL Number | MFCD02683961 |
| Handling | Protect from light and moisture |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
A highly potent ATP-noncompetitive MEK inhibitor. It inhibits MEK with an in vitro IC₅₀ of 1-1.3 nM. It does not inhibit other kinases. Highly recommended tool to inhibit MKK1 or MKK1 plus MKK5.
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