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PD184352

A MEK inhibitor
Catalog #: 1585
SKU-Size Size Price Qty
1585-25 25 mg
$795.00
1585-5 5 mg
$280.00
1585-1 1 mg
$75.00
More Sizes Get Quote

Product Details

Alternate Name CI-1040
Appearance Crystalline solid
CAS # 212631-79-3
Molecular Formula C₁₇H₁₄ClF₂IN₂O₂
Molecular Weight 478.67
Purity ≥99% by HPLC
Solubility DMSO (600 mg/ml)
SMILES C1CC1CONC(=O)C2=C(C(=C(C=C2)F)F)NC3=C(C=C(C=C3)I)Cl
InChi InChI=1S/C17H14ClF2IN2O2/c18-12-7-10(21)3-6-14(12)22-16-11(4-5-13(19)15(16)20)17(24)23-25-8-9-1-2-9/h3-7,9,22H,1-2,8H2,(H,23,24)
InChi Key GFMMXOIFOQCCGU-UHFFFAOYSA-N
PubChem CID 6918454
MDL Number MFCD02683961
Handling Protect from light and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A highly potent ATP-noncompetitive MEK inhibitor. It inhibits MEK with an in vitro IC₅₀ of 1-1.3 nM. It does not inhibit other kinases. Highly recommended tool to inhibit MKK1 or MKK1 plus MKK5.


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