Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

PD-166285 dihydrochloride

A potent, ATP-competitive and broadly active protein tyrosine kinase inhibitor
Catalog #: B2094

In stock

SKU-Size Size Price Qty
B2094-5 5 mg
B2094-25 25 mg
More Sizes Get Quote

Product Details

Alternate Name 6-(2,6-Dichlorophenyl)-2-[[4-[2-(diethylamino)ethoxy]phenyl]amino]-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one dihydrochloride
Appearance Yellow solid
CAS # 212391-63-4
Molecular Formula C₂₆H₂₇Cl₂N₅O₂.2HCl
Molecular Weight 612.37
Purity ≥98% by HPLC
Solubility DMSO (>40 mg/ml)
InChi InChI=1S/C26H27Cl2N5O2.2ClH/c1-4-33(5-2)13-14-35-19-11-9-18(10-12-19)30-26-29-16-17-15-20(25(34)32(3)24(17)31-26)23-21(27)7-6-8-22(23)28;;/h6-12,15-16H,4-5,13-14H2,1-3H3,(H,29,30,31);2*1H
PubChem CID 9916391
MDL Number MFCD18086890
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


PD-166285 is a potent, ATP-competitive and broadly active protein tyrosine kinase inhibitor. It inhibits tyrosine kinases c-Src, fibroblast growth factor receptor 1 (FGFR1), and platelet-derived growth factor receptor β(PDGFRβ) (IC₅₀ values are 8.4, 39.3 and 98.3 nM respectively). PD-166285 also displays inhibitory activity against mitogen-activated protein kinase (IC₅₀ = 5 μM) and protein kinase C (IC₅₀ = 22.7 μM).

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.