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PCI 34051

A potent HDAC8 inhibitor
Catalog #: 2251
SKU-Size Size Price Qty
2251-5 5 mg
$85.00
2251-25 25 mg
$325.00
More Sizes Get Quote

Product Details

Alternate Name N-​hydroxy-​1-​[(4-​methoxyphenyl)methyl]-​1H-​indole-​6-​carboxamide
Appearance White to Off-white Solid
CAS # 950762-95-5
Molecular Formula C₁₇H₁₆N₂O₃
Molecular Weight 296.32
Purity ≥95% by HPLC
Solubility DMSO (>20 mg/ml)
SMILES COC1=CC=C(C=C1)CN2C=CC3=C2C=C(C=C3)C(=O)NO
InChi InChI=1S/C17H16N2O3/c1-22-15-6-2-12(3-7-15)11-19-9-8-13-4-5-14(10-16(13)19)17(20)18-21/h2-10,21H,11H2,1H3,(H,18,20)
InChi Key AJRGHIGYPXNABY-UHFFFAOYSA-N
PubChem CID 24753719
MDL Number MFCD11114393
Handling Protect from light and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

PCI 34051 is a potent histone deacetylase 8 (HDAC8) inhibitor (IC₅₀ = 0.01 μM) with >200-fold selectivity over HDAC isoforms 1, 2, 3, 6, and 10 (IC₅₀s = 4, >50, >50, 2.9, and 13 μM, respectively).


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