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PBR Antibody

based on 1 citations in multiple journalsPBR Antibody14.1 4
Catalog #: 3044
SKU-Size Size Price Qty
3044-30T 30 µg
$89.00
3044-100 100 µg
$300.00
More Sizes Get Quote

Product Details

Antibody Target PBR
Alternate Name peripheral-type benzodiazepine receptor
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide surrounding amino acid 81 of mouse PBR
Accession # BAA04749
Gene ID 2257
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation In phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal
Purification Affinity purified
Species Reactivity Human, mouse, rat
Application Western blot, Immunohistochemistry
Application & Usage Western blot analysis (0.5-4 µg/ml) and Immunohistochemistry (10-20 µg/ml). However, the optimal conditions should be determined individually.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

PBR (Peripheral-type Benzodiazepine Receptor) is a ubiquitous protein (18 kDa) found in most steroidogenic tissues. It is located primarily in the outer mitochondrial membrane of steroid-producing tissues and is found in association with a 34 kDa voltage-dependent anion channel protein (VDAC). PBR is involved in the regulation of cholesterol transport from the outer to the inner mitochondrial membrane. It is thoμght to be part of the mitochondrial permeability transition pore (PT) and to be involved in apoptosis.


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Ji B et al (2008) J. Neurosci.: 12255 - 12267.
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