Product Details
| Alternate Name | (1aR-[1aR*,4E,7aS*,-10aS*,-10bR*])-2,3-6,7,7a,8,10a,10b-octahydro-1a,5-dimethyl-8-methyleneoxireno[9,10]cyclo deca[1,2-b]furan-9(1aH)-one |
|---|---|
| Appearance | White to off-white solid |
| CAS # | 20554-84-1 |
| Molecular Formula | C₁₅H₂₀O₃ |
| Molecular Weight | 248.32 |
| Purity | ≥97% by TLC |
| Solubility | DMSO (100 mg/ml) or EtOH (20 mg/ml) |
| SMILES | CC1=CCCC2(C(O2)C3C(CC1)C(=C)C(=O)O3)C |
| InChi | InChI=1S/C15H20O3/c1-9-5-4-8-15(3)13(18-15)12-11(7-6-9)10(2)14(16)17-12/h5,11-13H,2,4,6-8H2,1,3H3/b9-5+/t11-,12-,13+,15+/m0/s1 |
| InChi Key | KTEXNACQROZXEV-PVLRGYAZSA-N |
| PubChem CID | 7251185 |
| MDL Number | MFCD00134592 |
| Handling | Protect from air and light |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
An anti-inflammatory agent. Specifically inhibits activation of NF-κB by preventing the degradation of IκBα and IκBβ. Inhibits activation of MAP kinase (MAPK/ERK) and generation of leukotriene B4 and thromboxane B2. Potent anticancer agent. Induces apoptosis in various cancer cell lines. Specifically inhibits histone deacetylase 1 (HDAC1) without affecting other class I/II HDACs.
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