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A potent S100A9 inhibitor
Catalog #: B2617
SKU-Size Size Price Qty
B2617-5 5 mg
B2617-25 25 mg
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Product Details

Alternate Name ABR‑215757, ABR215757, N,5-diethyl-4-hydroxy-1-methyl-2-oxo-N-phenyl-1,2-dihydroquinoline-3-carboxamide
Appearance White to off-white solid
CAS # 248282-01-1
Molecular Formula C₂₁H₂₂N₂O₃
Molecular Weight 350.42
Purity ≥98% by HPLC
Solubility >50 mg/ml in DMSO
InChi InChI=1S/C21H22N2O3/c1-4-14-10-9-13-16-17(14)19(24)18(20(25)22(16)3)21(26)23(5-2)15-11-7-6-8-12-15/h6-13,24H,4-5H2,1-3H3
PubChem CID 54684617
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Paquinimod is a small molecule quinoline-3-carboxamide derivative that acts as a S100A9 inhibitor. It targets the S100A9 protein and disrupts its binding to the pro-inflammatory receptors, Receptor for Advanced Glycation Endproducts (RAGE) and Toll-like Receptor 4 (TLR4). Both RAGE and TLR4 are involved in the pathogenesis of many autoimmune and inflammatory diseases and paquinimod has shown convincing beneficial effects in several autoimmune/inflammatory disease models.

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