PANoptosis Pathway
PANoptosis is a unique inflammatory programmed cell death pathway involving a cytoplasmic multiprotein complex called the PANoptosome to restrict the pathogen number (bacteria, viruses, fungi, etc) and developing the host defense. It triggers pyroptosis, apoptosis, and necroptosis by activating RIPK, CASP-8, NLRP3 inflammasome, etc. This pathway helps in understanding the host-pathogen evolution to aid the discovery of new treatment strategies for infectious diseases. BioVision offers a variety of useful tools for your research in this area.
Click on the Targets for product details.
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ASC product(s):
• ASC Blocking Peptide (Cat#: 3291BP)
• ASC/TMS1 Antibody (Cat#: 3291)
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APOPTOSIS product(s):
• Apoptosis activator 2 (Cat#: 2784)
• Apoptosis inhibitor(Cat#: 2783)
• Mitochondrial Apoptosis Detection Fluorometric Kit, MitoCapture(Cat#: K250)
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Necroptosis product(s):
• Nec-1s (Cat#: 2263)
• Necrosulfonamide(Cat#: 9635)
• EZSolution™ Necrosulfonamide, Sterile-Filtered(Cat#: B1220)
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RIPK3 product(s):
• GSK'872 (Cat#: 2673)
• EZSolution™ GSK'872(Cat#: B1501)
• RIP3 Antibody(Cat#: 3293)
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Kinase product(s):
• RIPA-56 (Cat#: B3051)
• RIP Antibody(Cat#: 3279)
• RIP3 Antibody(Cat#: 3293)
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CARD product(s):
• Instant Lentivirus Detection Card (Cat#: K1470)
• Coronavirus IgM/IgG Antibody Detection Card(Cat#: K1463)
• ASC Blocking Peptide(Cat#: 3291BP)
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CARD product(s):
• Instant Lentivirus Detection Card (Cat#: K1470)
• Coronavirus IgM/IgG Antibody Detection Card(Cat#: K1463)
• ASC Blocking Peptide(Cat#: 3291BP)
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Caspase product(s):
• Caspase Fluorometric Substrate Set II Plus (Cat#: K137)
• Caspase Colorimetric Substrate Set II Plus(Cat#: K138)
• Caspase Colorimetric Substrate Set Plus(Cat#: K136)
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Caspase product(s):
• Caspase Fluorometric Substrate Set II Plus (Cat#: K137)
• Caspase Colorimetric Substrate Set II Plus(Cat#: K138)
• Caspase Colorimetric Substrate Set Plus(Cat#: K136)
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Caspase product(s):
• Caspase Fluorometric Substrate Set II Plus (Cat#: K137)
• Caspase Colorimetric Substrate Set II Plus(Cat#: K138)
• Caspase Colorimetric Substrate Set Plus(Cat#: K136)
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CASP1 product(s):
• Anti-Cleaved-Caspase-1 Antibody (Cat#: A1004)
• Caspase-1 (CASP1) (Human) ELISA Kit(Cat#: E4588)
• Caspase-1 (CASP1) (Rat) ELISA Kit(Cat#: E4594)
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CASP6 product(s):
• Caspase-6, human recombinant (Cat#: 1086)
• Caspase-6 Antibody ELISA Kit(Cat#: 3256)
• Caspase-6 (Active) Antibody(Cat#: 3156)
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CASP8 product(s):
• Caspase-8 (Human) ELISA Kit (Cat#: E4290)
• Caspase-8, human recombinant(Cat#: 1088)
• Caspase-8 Antibody(Cat#: 3158)
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Pyroptosis product(s):
• Talabostat mesylate (Cat#: B2061)
• EZSolution™ INF39(Cat#: B2530)
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LRR product(s):
• NLRP3 (Human) ELISA Kit (Cat#: E4890)
• Anti-NLRP3 Antibody(Cat#: A1767)
• Human CellExp™ LRRC4 /NGL-2, human recombinant(Cat#: 7461)
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PYRIN product(s):
• NLRP3 (Human) ELISA Kit (Cat#: E4890)
• Anti-NLRP3 Antibody(Cat#: A1767)
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PYRIN product(s):
• NLRP3 (Human) ELISA Kit (Cat#: E4890)
• Anti-NLRP3 Antibody(Cat#: A1767)
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DED product(s):
• DEDAF Antibody (Cat#: 3313)
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DED product(s):
• DEDAF Antibody (Cat#: 3313)
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RHIM product(s):
• RIP Antibody (Cat#: 3279)
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RHIM product(s):
• RIP Antibody (Cat#: 3279)
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RHIM product(s):
• RIP Antibody (Cat#: 3279)
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NLRP3 product(s):
• NLRP3 (Human) ELISA Kit (Cat#: E4890)
• Anti-NLRP3 Antibody(Cat#: A1767)
• EZSolution™ INF39(Cat#: B2530)
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