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PAK7, Active

Target for the small GTP binding proteins
Catalog #: 7727
$295.00

Product Details

Cat # +Size 7727-5
Size 5 μg
Alternate Name PAK7, Serine/threonine-protein kinase PAK 7
Gene Symbol PAK7
Gene ID 57144
Accession # Q9P286
Source Baculovirus (Sf9 insect cells)
Appearance Liquid
Physical Form Description Recombinant protein in storage buffer (50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol).
Molecular Weight 130.0 kDa
Purity by SDS-PAGE ≥75%
Handling Centrifuge the vial prior to opening.
Storage Conditions -80°C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not to be used in humans

Details

The p21-activated kinase (PAK) family of protein kinases has recently attracted considerable attention as an effector of Rho family of small G proteins and as an upstream regulator of MAPK signalling pathways during cellular events such as re-arrangement of the cytoskeleton and apoptosis. PAK7 is a novel human PAK family kinase that contains a CDC42/Rac1 interactive binding (CRIB) motif at the N-terminus and a Ste20-like kinase domain at the C-terminus. PAK7 like the other Paks has been implicated in the regulation of cell morphology, motility and transformation.


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