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PAK5/PAK7 Antibody

Catalog #: 3928
SKU-Size Size Price Qty
3928-30T 30 µg
$89.00
3928-100 100 µg
$245.00
More Sizes Get Quote

Product Details

Antibody Target PAK5/PAK7
Alternate Name Serine/threonine-protein kinase PAK 7; p21-activated kinase 7; PAK-7; p21-activated kinase 5; PAK-5.
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide surrounding amino acid 90 of human PAK5/PAK7
Accession # BAG53104
Gene ID 57144
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit anti-human PAK5/PAK7 polyclonal antibody in phosphate (PBS, pH 7.2) containing 30% glycerol, 0.5 % BSA and 0.01% thimerosal.
Purification Affinity purified
Species Reactivity Human, mouse, rat, dog
Application Western blot
Application & Usage Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~80 kDa of Pak5/PAK7 from samples of human, mouse, rat and dog origins. Reactivity to other species has not been determined.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

The PAK (p21-activated kinase) family of serine/threonine kinases plays an important role in multiple cellular processes, including cytoskeletal reorganization, MAPK signaling, apoptotic signaling, etc. PAK 5 is known for promoting neurite outgrowth and thus predominantly expressed in the brain. PAK 5 contains CDC42/Rac1and has shown to bind CDC42 in the presence of GTP. PAK 5 also plays an important role in inhibiting apoptotic cascade throμgh BAD phosphorylation.


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