Anti-PAD2 Polyclonal Antibody

Potentially involved in autoimmune diseases
Catalog #: A2322 | abID:

Product Details

Alternate Name Peptidyl Arginine Deiminase 2; PDI2; Protein-Arginine Deiminase Type II; EC; KIAA0994; PAD-H19; PADI2
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Recombinant Human PAD2 protein (amino acids 1 to 665)
Accession # Q9Y2J8
Gene ID 11240
Formulation 0.01 M PBS, pH 7.4 with 50% glycerol, 0.03% Proclin 300
Purification Protein G purification
Species Reactivity Human
Application Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Protein arginine deiminases (PADs) are a family of guanidine-modifying enzymes that catalyze the post-translational modification of target proteins by converting arginine to citrulline. Excessive citrullination of proteins may result in disease states. PAD2 is the most widely expressed and evolutionarily conserved family member. Known substrates for PAD2 include myelin basic protein and vimentin, and PAD2 is thought to play a role in the onset and progression of neurodegenerative diseases such as Alzheimer's and multiple sclerosis. PAD2 may also play a role in transcriptional regulation as it is capable of citrullinating histone H3.

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