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Anti-PAD1 Polyclonal Antibody

Catalyzes the conversion of arginine into citrulline in distinct proteins
Catalog #: A2321
SKU-Size Size Price Qty
A2321-50 50 µg
$195.00
A2321-100 100 µg
$365.00
More Sizes Get Quote

Product Details

Antibody Target Human PAD1
Alternate Name Peptidyl Arginine Deiminase 1; PDI1; Protein-Arginine Deiminase Type I; Peptidylarginine Deiminase I; HPAD-Colony 10; EC 3.5.3.15; HPAD10; PDI; PADI1
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PADI1
Accession # Q9ULC6
Gene ID 29943
Appearance Liquid
Formulation In PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
Purification Affinity purification
Species Reactivity Human, Mouse
Application Western Blotting
Handling The antibody solution should be gently mixed before use
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Protein arginine deiminases (PADs) are guanidine-modifying enzymes that catalyze the post-translational modification of target proteins by converting arginine to citrulline. Excessive citrullination of proteins may result in disease states. PAD1 is expressed in uterus and throughout the epidermis, and is involved in the late stages of epidermal differentiation and possibly hair follicle formation. Disruption in PAD1 activity is associated with certain skin diseases and Laing Distal Myopathy.


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