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Anti-PAD1 Monoclonal Antibody (Clone 6B4)

Catalyzes the conversion of arginine into citrulline in distinct proteins
Catalog #: A2311
SKU-Size Size Price Qty
A2311-50 50 µg
$295.00
A2311-100 100 µg
$475.00
More Sizes Get Quote

Product Details

Antibody Target Human PAD1
Alternate Name Peptidyl Arginine Deiminase 1; PDI1; Protein-Arginine Deiminase Type I; Peptidylarginine Deiminase I; HPAD-Colony 10; EC 3.5.3.15; HPAD10; PDI; PADI1
Host Mouse
Antibody Type Monoclonal
Isotype Mouse IgG2b
Immunogen Recombinant human PAD1 protein
Accession # Q9ULC6
Gene ID 29943
Appearance Liquid
Formulation In PBS, pH 7.2, 50% glycerol, 0.1% BSA, 0.02% sodium azide
Purification Protein G purification
Species Reactivity Human
Application Western Blotting, ELISA
Handling The antibody solution should be gently mixed before use
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Protein arginine deiminases (PADs) are guanidine-modifying enzymes that catalyze the post-translational modification of target proteins by converting arginine to citrulline. Excessive citrullination of proteins may result in disease states. PAD1 is expressed in uterus and throughout the epidermis, and is involved in the late stages of epidermal differentiation and possibly hair follicle formation. Disruption in PAD1 activity is associated with certain skin diseases and Laing Distal Myopathy.


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