Product Details
| Alternate Name | 1-[5-[(2,3-Dichlorophenyl)thio]-4-nitro-2-thienyl]ethanone |
|---|---|
| Appearance | White solid |
| CAS # | 882257-11-6 |
| Molecular Formula | C₁₂H₇Cl₂NO₃S₂ |
| Molecular Weight | 348.22 |
| Purity | ≥98% by TLC |
| Solubility | DMSO (~20 mg/ml, warm) or EtOH (~40 mg/ml, warm) |
| SMILES | CC(=O)C1=CC(=C(S1)SC2=C(C(=CC=C2)Cl)Cl)[N+](=O)[O-] |
| InChi | InChI=1S/C12H7Cl2NO3S2/c1-6(16)10-5-8(15(17)18)12(20-10)19-9-4-2-3-7(13)11(9)14/h2-5H,1H3 |
| InChi Key | LKZLGMAAKNEGCH-UHFFFAOYSA-N |
| PubChem CID | 2819993 |
| Handling | Protect from air and moisture |
| Storage Conditions | -20 ̊C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Cell-permeable. A Selective inhibitor of the ubiquitin-specific protease USP7 (IC₅₀ = 4.2 µM). Induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance. Displays antiangiogenic activity in vivo.
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