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Oxamflatin

A potent inhibitor of mammalian histone deacetylases (HDACs)
Catalog #: 2250
SKU-Size Size Price Qty
2250-1 1 mg
$85.00
2250-5 5 mg
$325.00
More Sizes Get Quote

Product Details

Alternate Name N-​hydroxy-​5-​[3-​[(phenylsulfonyl)amino]phenyl]-​2E-​penten-​4-​ynamide; Metacept 3
Appearance White to Off-white Solid
CAS # 151720-43-3
Molecular Formula C₁₇H₁₄N₂O₄S
Molecular Weight 342.37
Purity ≥95%
Solubility DMSO (5 mg/ml) or EtOH (0.5 mg/ml)
SMILES C1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC(=C2)C#CC=CC(=O)NO
InChi InChI=1S/C17H14N2O4S/c20-17(18-21)12-5-4-7-14-8-6-9-15(13-14)19-24(22,23)16-10-2-1-3-11-16/h1-3,5-6,8-13,19,21H,(H,18,20)/b12-5+
InChi Key QRPSQQUYPMFERG-LFYBBSHMSA-N
PubChem CID 5353852
MDL Number MFCD00949087
Handling Protect from light and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A potent inhibitor of mammalian histone deacetylases (HDACs) (IC₅₀ = 15.7 nM). A novel antitumor agent; oxamflatin modifies epigenetic status and gene expression, increases blastocyst quality, and subsequently enhances the nuclear reprogramming and developmental potential of SCNT (somatic cell nuclear transfer) embryos.


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