Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]



A potent inhibitor of 11β-hydroxylase and aldosterone synthase
Catalog #: B3108
SKU-Size Size Price Qty
B3108-5 5 mg
B3108-25 25 mg
More Sizes Get Quote

Product Details

Alternate Name LCI699; 4-[(5R)-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl]-3-fluorobenzonitrile
Appearance White powder
CAS # 928134-65-0
Molecular Formula C₁₃H₁₀FN₃
Molecular Weight 227.24
Purity ≥ 98%
Solubility ~45 mg/ml in DMSO
InChi InChI=1S/C13H10FN3/c14-12-5-9(6-15)1-3-11(12)13-4-2-10-7-16-8-17(10)13/h1,3,5,7-8,13H,2,4H2/t13-/m1/s1
PubChem CID 44139752
MDL Number MFCD25976825
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Osilodrostat is a potent inhibitor of the enzymes 11β-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2), which catalyze the final steps of cortisol and aldosterone biosynthesis, respectively, in the adrenal cortex. Osilodrostat inhibits 11β-hydroxylase and aldosterone synthase with IC₅₀ values of 2.5 nM and 0.7 nM respectively. It is used to lower cortisol levels in the treatment of Cushing's disease.

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.