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A potent EGFR tyrosine kinase inhibitor
Catalog #: B2201

In stock

SKU-Size Size Price Qty
B2201-1 1 mg
B2201-5 5 mg
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Product Details

Alternate Name 2-[4-(3-ethynylanilino)-7-(2-methoxyethoxy)quinazolin-6-yl]oxyethanol, hydrochloride; CP-473420
Appearance Crystalline solid
CAS # 183320-51-6
Molecular Formula C₂₁H₂₂ClN₃O₄
Molecular Weight 415.87
Purity ≥98% by HPLC
Solubility DMSO (>5 mg/ml)
InChi InChI=1S/C21H21N3O4.ClH/c1-3-15-5-4-6-16(11-15)24-21-17-12-19(27-8-7-25)20(28-10-9-26-2)13-18(17)22-14-23-21;/h1,4-6,11-14,25H,7-10H2,2H3,(H,22,23,24);1H
PubChem CID 18924996
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


OSI-420 is an active metabolite of Erlotinib (Cat. No. 1588) which is an orally active EGFR tyrosine kinase inhibitor with IC₅₀ of 2 and 20 nM for the inhibition of human EGFR and EGFR autophosphorylation in tumor cells

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