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OSI-930

A Kit, KDR, Flt, CSF-1R, c-Raf and Lck Inhibitor
Catalog #: B1712
SKU-Size Size Price Qty
B1712-5 5 mg
$145.00
B1712-25 25 mg
$575.00
More Sizes Get Quote

Product Details

Alternate Name OSI-930; OSI930; OSI 930; 3-((quinolin-4-ylmethyl)amino)-N-(4-(trifluoromethoxy)phenyl)thiophene-2-carboxamide
Appearance Solid
CAS # 728033-96-3
Molecular Formula C₂₂H₁₆F₃N₃O₂S
Molecular Weight 443.44
Purity >98%
Solubility DMSO
SMILES C1=CC=C2C(=C1)C(=CC=N2)CNC3=C(SC=C3)C(=O)NC4=CC=C(C=C4)OC(F)(F)F
InChi InChI=1S/C22H16F3N3O2S/c23-22(24,25)30-16-7-5-15(6-8-16)28-21(29)20-19(10-12-31-20)27-13-14-9-11-26-18-4-2-1-3-17(14)18/h1-12,27H,13H2,(H,28,29)
InChi Key FGTCROZDHDSNIO-UHFFFAOYSA-N
PubChem CID 9868037
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

OSI-930 is a potent inhibitor of receptor tyrosine kinases with IC50 values of 80 nM, 9 nM, 8 nM, 15 nM, 41 nM and 22 nM for c-Kit, KDR, Flt, CSF-1R, c-Raf and Lck respectively.


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