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OryzaExp™ Alpha-1 Antitrypsin, Human Recombinant

An acute-phase plasma protein
Catalog #: P1402

In stock

$345.00

Product Details

Cat # +Size P1402-100
Size 100 μg
Alternate Name Alpha-1 protease inhibitor, Alpha-1-antiproteinase, Serpin A1, AAT, PI
Gene Symbol SERPINA1
Gene ID 5265
Accession # AAB59375
Source Orzya sativa
Appearance Lyophilized powder
Physical Form Description Lyophilized
Molecular Weight 43.2 KDa
Purity by > 95%
Endotoxin Level ≤1EU/ug
Reconstitution Instructions Reconstitute in sterile PBS
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Alpha 1 Antitrypsin is an acute-phase plasma protein found at 290 mg per 100 ml. It functions as a serine protease inhibitor with targets like elastase, plasmin, collagenase, thrombin, leucocyte proteases, trypsin, chymotrypsin, and plasminogen activator. Clinically, its deficiency is associated with two major diseases: pulmonary emphysema and early onset/juvenile hepatic cirrhosis. It is elevated in inflammatory conditions, malignancies, liver disease and pregnancy and also after surgical trauma and use of oral contraceptives. The simultaneous quantitative determination of alpha-1-PI and ceruloplasmin permits differential diagnosis of liver afflictions. Rise in alpha 1 antitrypsin occurs as an acute phase response to tissue necrosis and inflammatio


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