Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]


A NLRP3 inflammasome inhibitor
Catalog #: B2358
SKU-Size Size Price Qty
B2358-5 5 mg
B2358-25 25 mg
More Sizes Get Quote

Product Details

Alternate Name Dapansutrile,3-(methylsulfonyl)-propanenitrile
Appearance White solid
CAS # 54863-37-5
Molecular Formula C₄H₇NO₂S
Molecular Weight 133.17
Purity ≥98%
Solubility >25 mg/ml (DMSO)
InChi InChI=1S/C4H7NO2S/c1-8(6,7)4-2-3-5/h2,4H2,1H3
PubChem CID 12714644
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


OLT-1177 is a potent and specific inhibitor of the NLRP3 inflammasome. It significantly decreases IL-1β and IL-18 levels in LPS-stimulated human blood-derived macrophages as well as IL-1β release and caspase-1 activity in human blood neutrophils with no effect on TNF-α levels.

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.