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A highly potent and selective PARP-inhibitor
Catalog #: 1952
SKU-Size Size Price Qty
1952-5 5 mg
1952-25 25 mg
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Product Details

Alternate Name 4-(3-(4-(cycloprppanecarbonyl)piperazine-1-carbonyl)-4-fluorobenzyl)phthalazine-1(2H)-one; ADZ-2281; KU-59436
Appearance White to off-white solid
CAS # 763113-22-0
Molecular Formula C₂₄H₂₃FN₄O₃
Molecular Weight 434.46
Purity ≥98% by HPLC
Solubility DMSO (~33 mg/ml) or EtOH (~ 1.7 mg/ml)
InChi InChI=1S/C24H23FN4O3/c25-20-8-5-15(14-21-17-3-1-2-4-18(17)22(30)27-26-21)13-19(20)24(32)29-11-9-28(10-12-29)23(31)16-6-7-16/h1-5,8,13,16H,6-7,9-12,14H2,(H,27,30)
PubChem CID 23725625
MDL Number MFCD13185161
Handling Protect from light and air
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Cell-permeable. A highly potent and selective PARP-inhibitor with IC₅₀ values of 5 nM and 1 nM for PARP-1 and PARP-2, respectively. Olaparib displays standalone activity in BRCA-1 deficient breast cancer cells.

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