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OG-L002

A potent and specific inhibitor of Lysine Specific Demethylase-1(LSD-1)
Catalog #: 9406
SKU-Size Size Price Qty
9406-5 5 mg
$165.00
9406-25 25 mg
$595.00
More Sizes Get Quote

Product Details

Alternate Name 4'-((1S,2R)-2-aminocyclopropyl)-[1,1'-biphenyl]-3-ol
Appearance White solid
CAS # 1357302-64-7
Molecular Formula C₁₅H₁₅NO
Molecular Weight 225.29
Purity ≥98% by HPLC
Solubility DMSO (>20 mg/ml)
SMILES C1C(C1N)C2=CC=C(C=C2)C3=CC(=CC=C3)O
InChi InChI=1S/C15H15NO/c16-15-9-14(15)11-6-4-10(5-7-11)12-2-1-3-13(17)8-12/h1-8,14-15,17H,9,16H2/t14-,15+/m1/s1
InChi Key DSOJSZXQRJGBCW-CABCVRRESA-N
PubChem CID 56639570
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

OG-L002 is a potent and specific inhibitor of Lysine Specific Demethylase-1(LSD-1) (IC₅₀ of 20 nM). Displays 36- and 69-fold selectivity over MAO-B and MAO-A, respectively. It potently represses herpes simplex virus (HSV) IE gene expression, genome replication, and reactivation from latency. OG-L002 suppresses primary lytic infection of HSV in vivo in a mouse model.


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