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OATD-01

A potent and selective chitinase inhibitor
Catalog #: B3334
SKU-Size Size Price Qty
B3334-1 1 mg
$85.00
B3334-5 5 mg
$335.00
More Sizes Get Quote

Product Details

Alternate Name 5-[4-[(2S,5S)-5-[(4-Chlorophenyl)methyl]-2-methyl-4-morpholinyl]-1-piperidinyl]-1H-1,2,4-triazol-3-amine OATD01
Appearance Solid
CAS # 2088453-21-6
Molecular Formula C₁₉H₂₇ClN₆O
Molecular Weight 390.92
Purity ≥98%
Solubility DMSO
SMILES C[[email protected]]1CN(C2CCN(C3=NN=C(N)N3)CC2)[[email protected]@H](CC4=CC=C(Cl)C=C4)CO1
InChi InChI=1S/C19H27ClN6O/c1-13-11-26(17(12-27-13)10-14-2-4-15(20)5-3-14)16-6-8-25(9-7-16)19-22-18(21)23-24-19/h2-5,13,16-17H,6-12H2,1H3,(H3,21,22,23,24)/t13-,17-/m0/s1
InChi Key STWVLEKJQQRGMO-GUYCJALGSA-N
PubChem CID 126642132
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

OATD-01 is a small molecule inhibitor of acidic mammalian chitinase (AMCase) (IC50 = 9 nM) and chitotriosidase (CHIT1) (IC50 = 26 nM). OATD-01 displays robust anti-fibrotic activity in multiple animal models


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