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OAC1

An Oct-4 activator
Catalog #: B1079
SKU-Size Size Price Qty
B1079-5 5 mg
$95.00
B1079-25 25 mg
$375.00
More Sizes Get Quote

Product Details

Alternate Name N-(1H-pyrrolo[2,3-c]pyridin-5-yl)benzamide
Appearance Beige solid
CAS # 300586-90-7
Molecular Formula C₁₄H₁₁N₃O
Molecular Weight 237.26
Purity ≥98% by HPLC
Solubility DMSO (>30 mg/ml) or EtOH (>20 mg/ml)
SMILES C1=CC=C(C=C1)C(=O)NC2=NC=C3C(=C2)C=CN3
InChi InChI=1S/C14H11N3O/c18-14(10-4-2-1-3-5-10)17-13-8-11-6-7-15-12(11)9-16-13/h1-9,15H,(H,16,17,18)
InChi Key HWJRIFZDXJKJJN-UHFFFAOYSA-N
PubChem CID 789882
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

OAC1 is an Oct4-activating compound that activates expression through the Oct4 gene promoter. In cells expressing Oct4 with Sox2, Klf4, and c-Myc, OAC1 (1 μM) enhances reprogramming efficiency by increasing the rate of production of induced pluripotent stem cells (iPSCs) from embryonic fibroblasts. OAC1 also upregulates mRNA expression of Oct-4, Sox-2 and Nanog, as well as Tet1.


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