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NT5C3B, human recombinant

Catalog #: P1040
SKU-Size Size Price Qty
P1040-20 20 μg
$105.00
P1040-100 100 μg
$495.00
More Sizes Get Quote

Product Details

Alternate Name NT5C3L, 7-methylguanosine phosphate-specific 5'-nucleotidase
Gene Symbol NT5C3B
Gene ID 115024
Accession # Q969T7
Source E. coli
Appearance Liquid
Physical Form Description Phosphate Buffered Saline (pH7.4) containing 20% glycerol, 1mM DTT
Molecular Weight 36.8 kDa
Purity by SDS-PAGE > 85%
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSMAEEVST LMKATVLMRQ PGRVQEIVGA LRKGGGDRLQ VISDFDMTLS RFAYNGKRCP SSYNILDNSKIISEECRKEL TALLHHYYPI EIDPHRTVKE KLPHMVEWWT KAHNLLCQQK IQKFQIAQVV RESNAMLREG YKTFFNTLYH NNIPLFIFSAGIGDILEEII RQMKVFHPNI HIVSNYMDFN EDGFLQGFKG QLIHTYNKNS SACE
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

NT5C3B, also known 7-methylguanosine phosphate-specific 5'-nucleotidase, includes transferase activity and nucleotide binding. Among its related super-pathways are adenosine nucleotides degradation II and Pyrimidine metabolism. Specifically it hydrolyzes 7-methylguanosine monophosphate (m(7)GMP) to 7- methylguanosine and inorganic phosphate. The specific activity for m(7)GMP may protect cells against undesired salvage of m(7)GMP and its incorporation into nucleic acids. Also it has weak activity for CMP. Recombinant human NT5C3B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography


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