Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

New

NQTrp

A potent inhibitor of amyloid β aggregation
Catalog #: B2981
SKU-Size Size Price Qty
B2981-5 5 mg
$95.00
B2981-25 25 mg
$380.00
More Sizes Get Quote

Product Details

Alternate Name N-(1,4-Dihydro-1,4-dioxo-2-naphthalenyl)-L-tryptophan; (2S)-2-[(1,4-dioxonaphthalen-2-yl)amino]-3-(1H-indol-3-yl)propanoic acid; 1,4-naphthoquinon-2-yl-l-tryptophan
Appearance Orange to Dark Orange-Red powder
CAS # 185351-19-3
Molecular Formula C₂₁H₁₆N₂O₄
Molecular Weight 360.36
Purity 98%
Solubility ~1 mg/ml in Ethanol, ~20 mg/ml in DMSO and DMF
SMILES C1=CC=C2C(=C1)C(=O)C=C(C2=O)NC(CC3=CNC4=CC=CC=C43)C(=O)O
InChi InChI=1S/C21H16N2O4/c24-19-10-17(20(25)15-7-2-1-6-14(15)19)23-18(21(26)27)9-12-11-22-16-8-4-3-5-13(12)16/h1-8,10-11,18,22-23H,9H2,(H,26,27)/t18-/m0/s1
InChi Key DZZUYZXINNHEGM-SFHVURJKSA-N
PubChem CID 56605052
MDL Number MFCD21496345
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.

Details

NQTrp is an inhibitor of amyloid β (Aβ) oligomerization and fibrillization, with an IC₅₀ of 50 nM for formation of fibrils from Aβ1-42. It reduces the cytotoxic effect of Aβ oligomers in rat PC12 neuronal cell line. It also increases the life span and completely abolishes defective locomotion in a transgenic Alzheimer's disease Drosophila model.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.