A potent inhibitor of protein phosphatase types 1 (PP1) and 2A (PP2A)
Catalog #: 2094 | abID:

Product Details

Cat # +Size 2094-50
Size 50 μg
Alternate Name Cyclo[3S-​amino-​9S-​methoxy-​2S,​6E,​8S-​trimethyl-​10-​phenyl-​4,​6-​ decadienoyl-​D-​γ-​glutamyl-​(2Z)-​2-​(methylamino)-​2-​butenoyl-​(3S)-​ 3-​methyl-​D-​β-​aspartyl-​L-​arginyl]
Appearance Liquid
Formulation In Ethanol
CAS # 118399-22-7
Molecular Formula C₄₁H₆₀N₈O₁₀
Molecular Weight 824.96
Purity ≥95%
InChi InChI=1S/C41H60N8O10/c1-8-31-38(54)48-34(40(57)58)26(5)36(52)46-29(15-12-20-44-41(42)43)37(53)45-28(25(4)35(51)47-30(39(55)56)18-19-33(50)49(31)6)17-16-23(2)21-24(3)32(59-7)22-27-13-10-9-11-14-27/h8-11,13-14,16-17,21,24-26,28-30,32,34H,12,15,18-20,22H2,1-7H3,(H,45,53)(H,46,52)(H,47,51)(H,48,54)(H,55,56)(H,57,58)(H4,42,43,44)/b17-16+,23-21+,31-8+
PubChem CID 6437077
MDL Number MFCD16659855
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Nodularin is a hepatotoxic monocylic pentapeptide produced by cyanobacterium Nodularia spumigena. It is a potent inhibitor of protein phosphatase types 1 (PP1) and 2A (PP2A), exhibiting IC₅₀ values of 1.8 and 0.026 nM, respectively. It inhibits PP2B only at higher concentrations ( IC₅₀ = 1.8 µM).

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