Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

NMS-P118

A potent, and selective poly(ADP-ribose) polymerase 1 (PARP1) inhibitor
Catalog #: B2320

In stock

SKU-Size Size Price Qty
B2320-5 5 mg
$125.00
B2320-25 25 mg
$495.00
More Sizes Get Quote

Product Details

Alternate Name 2-[1-(4,4-difluorocyclohexyl)-4-piperidinyl]-6-fluoro-2,3-dihydro-3-oxo-1H-isoindole-4-carboxamide
Appearance Crystalline solid
CAS # 1262417-51-5
Molecular Formula C₂₀H₂₄F₃N₃O₂
Molecular Weight 395.42
Purity ≥98% by HPLC
Solubility >20 mg/ml in DMSO
SMILES C1CC(CCC1N2CCC(CC2)N3CC4=C(C3=O)C(=CC(=C4)F)C(=O)N)(F)F
InChi InChI=1S/C20H24F3N3O2/c21-13-9-12-11-26(19(28)17(12)16(10-13)18(24)27)15-3-7-25(8-4-15)14-1-5-20(22,23)6-2-14/h9-10,14-15H,1-8,11H2,(H2,24,27)
InChi Key ARYVAQSYRLZVQD-UHFFFAOYSA-N
PubChem CID 49843531
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A potent, and selective poly(ADP-ribose) polymerase 1 (PARP1) inhibitor. It is selective for PARP1 (Kd = 9 nM) over PARP2 (Kd = 1,390 nM). NMS-P118 displays anticancer activity as single agent, as well as in combination therapies.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.