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A potent, and selective poly(ADP-ribose) polymerase 1 (PARP1) inhibitor
Catalog #: B2320
SKU-Size Size Price Qty
B2320-5 5 mg
B2320-25 25 mg
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Product Details

Alternate Name 2-[1-(4,4-difluorocyclohexyl)-4-piperidinyl]-6-fluoro-2,3-dihydro-3-oxo-1H-isoindole-4-carboxamide
Appearance Crystalline solid
CAS # 1262417-51-5
Molecular Formula C₂₀H₂₄F₃N₃O₂
Molecular Weight 395.42
Purity ≥98% by HPLC
Solubility >20 mg/ml in DMSO
InChi InChI=1S/C20H24F3N3O2/c21-13-9-12-11-26(19(28)17(12)16(10-13)18(24)27)15-3-7-25(8-4-15)14-1-5-20(22,23)6-2-14/h9-10,14-15H,1-8,11H2,(H2,24,27)
PubChem CID 49843531
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


A potent, and selective poly(ADP-ribose) polymerase 1 (PARP1) inhibitor. It is selective for PARP1 (Kd = 9 nM) over PARP2 (Kd = 1,390 nM). NMS-P118 displays anticancer activity as single agent, as well as in combination therapies.

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