Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]


A potent, selective, allosteric inhibitor of the ATPase VCP/p97
Catalog #: 9600
SKU-Size Size Price Qty
9600-5 5 mg
9600-25 25 mg
More Sizes Get Quote

Product Details

Alternate Name (3-​[3-​(cyclopentylthio)​-​5-​[[[2-​methyl-​4'-​(methylsulfonyl)​[1,​1'-​biphenyl]​-​4-​yl]​oxy]​methyl]​-​4H-​1,​2,​4-​triazol-​4-​yl]​-pyridine
Appearance Off-white solid
CAS # 1418013-75-8
Molecular Formula C₂₇H₂₈N₄O₃S₂
Molecular Weight 520.67
Purity ≥98% by HPLC
Solubility DMSO (>10 mg/ml)
InChi InChI=1S/C27H28N4O3S2/c1-19-16-22(11-14-25(19)20-9-12-24(13-10-20)36(2,32)33)34-18-26-29-30-27(35-23-7-3-4-8-23)31(26)21-6-5-15-28-17-21/h5-6,9-17,23H,3-4,7-8,18H2,1-2H3
PubChem CID 71521142
MDL Number MFCD28009371
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


NMS-873 is a potent, selective, allosteric inhibitor of the ATPase VCP/p97 (IC₅₀ = 30 nM). NMS-873 activates the unfolded protein response, interferes with autophagy and induces cancer cell death. NMS-873 also inhibits proliferation of HCT116 cancer cell line cells with an IC₅₀ value of 400 nM.

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.