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NLG919

A potent inhibitor of indoleamine-2,3-dioxygenase (IDO)-pathway inhibitor
Catalog #: 9407
SKU-Size Size Price Qty
9407-5 5 mg
$115.00
9407-25 25 mg
$425.00
More Sizes Get Quote

Product Details

Alternate Name 1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanol; NLG-919
Appearance Off-white solid
CAS # 1402836-58-1
Molecular Formula C₁₈H₂₂N₂O
Molecular Weight 282.38
Purity ≥98% by HPLC
Solubility DMSO (~ 3 mg/ml)
SMILES C1CCC(CC1)C(CC2C3=CC=CC=C3C4=CN=CN24)O
InChi InChI=1S/C18H22N2O/c21-18(13-6-2-1-3-7-13)10-16-14-8-4-5-9-15(14)17-11-19-12-20(16)17/h4-5,8-9,11-13,16,18,21H,1-3,6-7,10H2
InChi Key YTRRAUACYORZLX-UHFFFAOYSA-N
PubChem CID 66558287
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

NLG919 is a potent inhibitor of indoleamine-2,3-dioxygenase (IDO)-pathway (Ki = 7 nM). Indoleamine 2,3-dioxygenase (IDO) is an enzyme with immune-suppressive properties that is commonly exploited by tumors to evade immune destruction.


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