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Nimustine hydrochloride

An anticancer agent
Catalog #: B2069

In stock

SKU-Size Size Price Qty
B2069-10 10 mg
$65.00
B2069-50 50 mg
$235.00
More Sizes Get Quote

Product Details

Alternate Name 3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-1-(2-chloroethyl)-1-nitrosourea hydrochloride; NSC-245,382; NSC245,382
Appearance White to yellow solid
CAS # 55661-38-6
Molecular Formula C₉H₁₄Cl₂N₆O₂
Molecular Weight 309.15
Purity ≥97%
Solubility DMSO (>20 mg/ml) or H₂O (>30 mg/ml)
SMILES CC1=NC=C(C(=N1)N)CNC(=O)N(CCCl)N=O.Cl
InChi InChI=1S/C9H13ClN6O2.ClH/c1-6-12-4-7(8(11)14-6)5-13-9(17)16(15-18)3-2-10;/h4H,2-3,5H2,1H3,(H,13,17)(H2,11,12,14);1H
InChi Key KPMKNHGAPDCYLP-UHFFFAOYSA-N
PubChem CID 91657
MDL Number MFCD01676942
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Nimustine is a nitrosourea compound that displays anticancer activity. Nimustine induces DNA cross-linking and double-stranded DNA breaks. Nimustine is clinically used to treat gliomas and may also downregulate expression of DNA ligase IV.


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