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A selective cyclooxygenase-2 (COX-2) inhibitor.
Catalog #: 2777
SKU-Size Size Price Qty
2777-1G 1 g
2777-5G 5 g
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Product Details

Alternate Name N-​(4-​Nitro-​2-​phenoxyphenyl)-​methanesulfonamide; R805
Appearance Yellow solid
CAS # 51803-78-2
Molecular Formula C₁₃H₁₂N₂O₅S
Molecular Weight 308.31
Purity ≥98%
Solubility DMSO (~30 mg/ml) or EtOH (~ 7 mg/ml)
SMILES CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2=CC=CC=C2
InChi InChI=1S/C13H12N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h2-9,14H,1H3
PubChem CID 4495
MDL Number MFCD00079470
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Nimesulide is a selective cyclooxygenase-2 (COX-2) inhibitor. The IC₅₀ values are 70 and 1.27 µM for human recombinant COX-1 and -2 (at 20 µM arachidonic acid), respectively, and 22 and 0.03 µM for ovine COX-1 and -2 (at 100 µM arachidonic acid), respectively.

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