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NGF-beta, human recombinant

A factor critical for the survival & maintenance of sympathetic and sensory neurons
Catalog #: 4303
SKU-Size Size Price Qty
4303-20 20 μg
4303-1000 1 mg
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Product Details

Alternate Name β Polypeptide, NGF, NGFB, HSAN5, β-NGF, MGC161426, MGC161428.
Gene Symbol NGF
Gene ID 4803
Accession # P01138
Source CHO cells
Appearance Lyophilized protein
Physical Form Description Sterile filtered and then lyophilized in 30 mM Sodium Acetate, pH 5.5 containing 1% HAS.
Molecular Weight 16.95 kDa
Purity by SDS-PAGE ≥98%
Purity by ≥98%
Endotoxin Level <0.1 ng/μg
Biological Activity The ED₅₀ as determined using PC12 cell line is 1.2-2 ng/ml and using DRG cell line is 0.8-1.5 ng/ml.
Reconstitution Instructions Reconstituted human NGF-β should be stored in working aliquots at -20°C. For long-term storage, it is recommended to add a carrier protein (0.1% HAS or BSA). Avoid freeze/thaw cycles.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans


Nerve growth factor-β (NGF-β) is a potent neurotrophic factor that supports the growth and survivability of nerve and/or glial cells. The active form of human NGF-β is a dimer, formed by two identical 119 amino acid subunits, which is held together by strong hydrophobic interactions. Recombinant human BGF-b produced in CHO cells is a homodimer, glycosylated, polypeptide chain containing 2 identical 119 amino acids and having a molecular weight of 16.95 kDa. The protein is purified by proprietary chromatographic techniques.

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